This is a page hosting polyaPeak, which is an R package for ranking ChIP-seq peaks with shape information. polyaPeak uses a Bayesian hierarchical model to incorporate the peak shapes in the ranking. The shapes are described by a mixture of multivariate Polya distributions. Real data analyses show that polyaPeak outperforms several popular peak calling software including MACS, CisGenome and PICS.

The R package source can be download at here. Following standard R package installation procedure to install in R. The package vignnette is distributed within the package, or can be found at here.